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Edward A. Kesicki, PhD

Edward A. Kesicki, PhD

Director, Small-Molecule Drug Discovery

Ed Kesicki is the Director of Small-Molecule Drug Discovery at IDRI. He is involved with two key areas of research within the organization. First, he oversees the design and synthesis of new small-molecule antibiotics for tuberculosis treatment. Second, he is designing processes to prepare fully synthetic vaccine adjuvants that act via Toll-like receptors in order to stimulate the immune system during vaccination.

An organic chemist by training, Ed has been in the drug discovery business since 1997. Ed cofounded the nonprofit Afya World Medicines, which was merged into IDRI in 2008 to focus on the discovery of new treatments for tuberculosis. Prior to Afya, Ed spent 9 years at Icos Corporation, working on several medicinal chemistry projects that delivered compounds that are currently in human studies (Chk1 kinase and PI3-kinase delta inhibitors). Ed is an inventor on over 20 patents in 5 target areas, an author on numerous peer-reviewed articles, and has been invited to speak at several national meetings.

Ed received his BS from Stanford University and earned his PhD in Organic Chemistry from the University of California, San Diego.

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