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Thomas Vedvick, PhD
Director, Process Sciences
Thomas Vedvick is the Director of Process Sciences at IDRI.
Tom's research interests are focused on the development of
large scale protein purification and the characterization of
proteins for vaccine development. In addition, Tom directs
the exciting adjuvant formulation program at IDRI. He has
more than 70 original articles, and holds 28 issued U.S.
patents for diagnostics, vaccines, and therapeutics of
infectious diseases and cancer.
Prior to joining IDRI, Tom worked at the Salk Institute
Biotechnology Industrial Associates (SIBIA) where he led the
protein purification and characterization laboratory. While at
SIBIA he collaborated on the development of the Pichia
pastoris recombinant protein expression system. Tom later
left SIBIA to work at Telios Pharmaceuticals, where he
developed peptide based products for wound healing. Tom
then joined Corixa Corporation where he established a
protein microsequencing facility and directed the process
development group which focused on vaccines for infectious
diseases and cancer. Afterwards, Tom spent two years
working at LigoCyte pharmaceuticals, where he served as
Director of Process Development and Project Leader in the
Norovirus vaccine program. He led the development of
purification methods, formulation, and cGMP contract
manufacturing of the Norovirus,Virus Like Particles. This
successful program was the first product that reached a
phase I clinical trial for LigoCyte Pharmaceutical.
Tom obtained his BSc in Chemistry from the University of
Puget Sound, his MSc in Chemistry from Western
Washington State University, and his PhD in Biochemistry
from Oregon Health Sciences University.
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