Antibiotic Resistance: Are You Contributing to the Problem?

November 16th, 2015|Blog, Drugs, Tuberculosis|

How many times have you been prescribed antibiotics and didn’t finish the course of treatment? Maybe you were feeling better or  thought “I could save the rest of these in case I get sick again.” If so, you are a contributor to the rise of antibiotic resistance — and you might not realize it. This week, Nov. 16-22, has been designated by the World Health Organization as “World Antibiotic Awareness Week,” designed to increase awareness of global antibiotic resistance and encourage best practices, such as completing a full course of antibiotics when prescribed and not sharing antibiotics prescribed for you with others. “The rise of antibiotic resistance is a global crisis. It’s one of the greatest threats to health today. This makes a broad range of common infections much more difficult to treat, replacement treatment are more costly, more toxic, and require much longer periods of time for treatment,” WHO director-general Dr. Margaret Chan said in a news conference. […]

The Silent Soldiers of War

May 21st, 2015|Drugs, Leishmaniasis, Malaria, News, Tuberculosis, Vaccines|

As Memorial Day arrives to herald the start of summer, it’s time to pause in remembrance of U.S. Armed Forces members who lost their lives during service to their country. And, over the course of time, hundreds of thousands of those lives were claimed by silent soldiers that have no loyalty to country or flag, with no respect for borders: infectious diseases. During the U.S. Civil War, disease claimed more lives than bullets; upwards of two-thirds of deaths in the war were attributed to disease. Smallpox, along with dysentery, typhoid fever, scarlet fever, measles, malaria, consumption (tuberculosis) and a host of other infectious diseases, cut a swath through soldiers on both sides. Often before they even faced their human enemies, soldiers were hit by a wave of infection,  soon after arrival in camp. Those from rural areas were most vulnerable, lacking the immunity to childhood diseases those from urban areas often had.  And, disease epidemics played a significant role in halting several major campaigns during the Civil War, with these delays prolonging the fighting by as much as two years. […]

Simple, Elegant Solution Holds Promise for Drug Resistance

January 9th, 2015|Drugs, News, Tuberculosis|

A lot of interest has been generated by a recent paper in Nature. Researchers have identified a new antibiotic that works against a wide range of bacterial species that cause infection, and resistance did not develop in the laboratory. The need for new antibiotics is great; many infections are now resistant to the drugs we have, and there has been a lack of effort in developing new ones. Much has been said about the reasons why, but one reason is because antibiotics don’t make enough money to cover the cost of developing them. However, it remains the case we urgently need new antibiotics for many infections, including the ones we work on at IDRI, like tuberculosis. Antibiotics are compounds produced by one living organism that kill another and in many cases they are produced by bacteria found in the environment, for example in water, soil, etc. In this research, the authors found a completely new antibiotic produced by a soil bacterium. […]

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