- Steven G. Reed, PhD - Head of Research & Development, IDRI Founder
- Curtis D. Malloy, JD, MPH - President
- Karen Kinch - Vice President, Administration
- Anna Marie Beckmann, PhD - Vice President, Development & Regulatory
- Rhea N. Coler, PhD - Vice President, Preclinical Biology
- Sharon Busby, PhD - Director, Project Management
- Darrick Carter, PhD - Director, Formulations
- Joshua Oluoch Odingo, PhD - Director, Chemistry
- Tanya Parish, PhD - Director, Drug Discovery
- Thomas Vedvick, PhD - Director, Process Sciences
- Franco M. Piazza, MD, MPH - Medical Director
- Edward A. Kesicki, PhD - Director, Small-Molecule Drug Discovery